P0300 on Nissan
Random/Multiple Cylinder Misfire Detected
P0300 on Nissan vehicles indicates random/multiple cylinder misfire detected. Au7o has documented this code across 8 Nissan models — most commonly on Altima, Armada, Frontier. P0300 means the engine computer detected misfires occurring randomly or across multiple cylinders rather than in one specific cylinder. A misfire is when a cylinder fails to ignite its fuel-air mixture properly, which the computer senses through small fluctuations in crankshaft speed. Because it's not isolated to one cylinder, the cause is usually something that affects the whole engine — like fuel, air, or ignition system problems — rather than a single coil or plug. Persistent or heavy misfiring wastes fuel, runs rough, and can damage the catalytic converter, which is why a flashing check engine light should be taken seriously. Typical repair costs on Nissan range from $50 to $9,000, depending on the specific model and root cause.
Common Causes of P0300
- •Worn or fouled spark plugs (across cylinders)
- •Vacuum or intake air leak
- •Weak fuel pump, clogged fuel filter, or low fuel pressure
- •Failing ignition coils or worn spark plug wires
- •Dirty or faulty mass airflow (MAF) sensor
- •Clogged or dirty fuel injectors
- •Faulty crankshaft/camshaft position sensor
- •Low compression or EGR/PCV system faults
P0300 on Nissan by Model
Nissan Altima(3 issues)
- 2.5L Pre-Catalyst Breakdown Causing Excessive Oil Consumption and Engine Damage2002-2006
On many 2.5L QR25DE Altimas, the pre-catalytic converter material can deteriorate and be drawn back into the engine during valve overlap, scoring cylinder walls and accelerating oil consumption. Owners report needing to add oil frequently, loss of compression, rough running, and in severe cases complete engine failure. This issue is widely discussed in owner communities and tied to Nissan service information addressing catalyst and ECM updates on affected 2.5L cars.
- QR25DE Ignition Coil Failures Causing Misfires (Cylinders 1 and 4)2002-2018
The 2.5L QR25DE four-cylinder is widely documented for repeated coil-on-plug ignition coil failures, with cylinders 1 and 4 (the end cylinders) failing most often. A failing coil triggers a single-cylinder misfire, rough idle, hesitation, and a flashing check engine light. Failures are frequently accelerated by oil leaking from the valve cover gasket / spark-plug tube seals saturating the coil boots, so coils can fail again soon after replacement if the oil leak is not addressed. A persistent misfire dumps raw fuel into the catalytic converter and can damage it.
- 2.5L QR25DE Head Gasket Failure Causing Coolant Loss and Overheating2002-2006
The first-generation-era 2.5L QR25DE (2002-2006) is well known for head gasket failure. Because the QR25 uses an open-deck block, the combustion ring of the gasket commonly fails into the combustion chamber, so owners often see disappearing coolant, overheating, and white exhaust smoke without the classic milky oil. Failures are frequently linked to the pre-catalyst breaking up and scoring cylinders (raising heat/pressure) and to the secondary block thermostat sticking closed. Left unrepaired it leads to chronic overheating and potential warped-head / engine damage.
Nissan Armada(1 issue)
- VVEL Solenoid Failure (VK56VD Engine)2017-2024
The 2017+ Armada uses the VK56VD 5.6L V8 with VVEL (Variable Valve Event and Lift) which is prone to solenoid and actuator failures. The VVEL solenoids can stick or fail, causing rough idle, misfires, and reduced power. This is a common issue shared with the Infiniti QX80. Replacement requires removing the intake manifold.
Nissan Frontier(2 issues)
- Timing Chain Rattle and Failure (QR25DE 4-Cylinder)2005-2012
The 4-cylinder QR25DE engine in the Frontier is prone to timing chain tensioner and guide failure, separate from the VQ40DE V6 issue. The primary timing chain tensioner loses pressure, allowing chain slack that causes a distinctive rattle on startup. If ignored, the chain can skip timing and cause valve damage. This issue typically manifests between 100,000-150,000 miles and is exacerbated by extended oil change intervals.
- Distributor / Ignition System Failure Causing Sudden Stall or No-Start2000-2004
A well-documented failure on first-generation Frontier V6 trucks is the distributor assembly, especially the internal cam/crank angle sensor and bearing wear inside the distributor. Owners report intermittent bucking, random stalling, hard starts, and eventual crank-no-start, often after the engine warms up. Nissan issued service information for distributor-related drivability faults, and owner complaint patterns are consistent across Frontier and related Xterra applications using the VG33E/VG33ER.
Nissan Maxima(1 issue)
- Ignition Coil Failure (VQ35DE)2004-2015
The VQ35DE engine in the 6th and 7th generation Maxima is prone to ignition coil failure. Coils typically fail one at a time, causing misfires on the affected cylinder. The rear bank (cylinders 1-3) coils fail more frequently due to heat soak from the firewall proximity. Coil failure is especially common after 60,000-80,000 miles and is one of the most reported Maxima issues.
Nissan Pathfinder(2 issues)
- VQ35DE Timing Chain Stretch and Guide Wear2013-2016
The 2013-2016 Pathfinder with the 3.5L VQ35DE engine develops timing chain stretch and chain guide wear, typically after 80,000-120,000 miles. The timing chain tensioner, secondary chain tensioners, and plastic chain guides all degrade over time. Stretched chains cause rattling on cold start, timing drift triggering misfire codes, and eventual engine failure if the chain jumps timing. The VQ35DE uses three chains (primary and two secondary), making replacement a complex job requiring 8-12 hours of labor. Infrequent oil changes accelerate chain and guide wear due to inadequate tensioner lubrication.
- Optical distributor failure (VG30E/VG33E) causing misfire, rough idle, stalling and no-start1990-1999
The V6 Pathfinders of this era use a camshaft-driven Hitachi distributor that houses the optical crank/cam position sensor and rotor inside a single unit. It is one of the most frequently reported failure points on the WD21 (1990-1995 VG30E) and early R50 (1996-1999 VG33E) trucks. Internal wear, a degrading optical disc, a failing internal coil, or the rotor-retaining screw working loose leads to intermittent or complete loss of spark and timing signal. Failures are often heat-related, showing up once the engine is warm and worsening under load.
Nissan Rogue(1 issue)
- 1.5L VC-Turbo Main/Link Bearing Seizure Causing Engine Knock, Stall, and Total Engine Failure (Recall)2021-2024
The variable-compression 1.5L VC-Turbo can suffer a manufacturing defect in the main, A-link, C-link, and L-link engine bearings. Higher-than-expected oil temperatures thin the oil and starve the bearings, leading to bearing seizure, rod knock, abnormal engine noise, hard/rough starts, stalling, and ultimately catastrophic engine failure (potentially while driving). NHTSA opened an investigation in December 2023; Nissan issued recall 25V-437 (June 2025, ~443,899 units, MY2021-2024) followed by 26V-080 (Feb 2026, ~323,917 units built Oct 2022-Nov 2024). Distinct from the already-covered PCV/oil-smell VC-Turbo issue — this is bottom-end bearing failure. Hundreds of warranty engine-replacement claims logged.
Nissan Sentra(2 issues)
- Excessive Oil Consumption (QR25DE)2007-2012
The 6th generation Sentra with the 2.5L QR25DE engine is known for excessive oil consumption, often burning 1 quart every 1,000-2,000 miles. The issue is caused by worn piston rings and valve stem seals. The QR25DE engine design has tight piston ring tolerances that contribute to oil passing into the combustion chamber. Nissan performed an oil consumption test for warranty claims but many vehicles were out of warranty when the issue became severe.
- GA16DE valve cover gasket and spark-plug-tube seal oil leak (oil in the plug wells)1991-1999
The GA16DE's valve cover gasket and its spark-plug-tube seals harden and leak with age and heat cycles. Oil weeps down the outside of the engine and, more importantly, pools inside the spark plug wells where it saturates the plug boots and can cause misfires and rough running. A partial gasket-only repair often doesn't hold once the tube seals have hardened. Nissan vehicles past ~75,000 miles are noted as substantially more likely to develop these cover/gasket leaks.
Nissan Versa(1 issue)
- Ignition Coil Failure2007-2019
The Versa HR16DE engine experiences ignition coil failure, typically one coil at a time. Failed coils cause misfires on the affected cylinder, resulting in rough running, loss of power, and increased emissions. The compact engine bay and heat soak contribute to coil degradation. Coils typically fail between 60,000-100,000 miles. Running on a failed coil can damage the catalytic converter from unburned fuel.
Looking for P0300 on a different make?
View P0300 across all makes →Frequently Asked Questions
What does P0300 mean on Nissan?▼
P0300 stands for "Random/Multiple Cylinder Misfire Detected." P0300 means the engine computer detected misfires occurring randomly or across multiple cylinders rather than in one specific cylinder. A misfire is when a cylinder fails to ignite its fuel-air mixture properly, which the computer senses through small fluctuations in crankshaft speed. Because it's not isolated to one cylinder, the cause is usually something that affects the whole engine — like fuel, air, or ignition system problems — rather than a single coil or plug. Persistent or heavy misfiring wastes fuel, runs rough, and can damage the catalytic converter, which is why a flashing check engine light should be taken seriously. On Nissan specifically, this code is documented across 8 models.
What causes P0300 on Nissan vehicles?▼
Common causes on Nissan: Worn or fouled spark plugs (across cylinders), Vacuum or intake air leak, Weak fuel pump, clogged fuel filter, or low fuel pressure, Failing ignition coils or worn spark plug wires, Dirty or faulty mass airflow (MAF) sensor. Specific causes vary by model and year — see the per-model sections below.
How much does it cost to fix P0300 on a Nissan?▼
Repair costs on Nissan range from $50 to $9,000, depending on the specific model and root cause.
Which Nissan models have P0300 documented?▼
Au7o has documented P0300 on 8 Nissan models: Altima, Armada, Frontier, Maxima, Pathfinder, Rogue, Sentra, Versa.