P0301 on GMC
Cylinder 1 Misfire Detected
P0301 on GMC vehicles indicates cylinder 1 misfire detected. Au7o has documented this code across 4 GMC models — most commonly on Canyon, Sierra 1500, Sierra 2500HD. P0301 means the engine computer detected a misfire specifically in cylinder 1 — the spark didn't ignite the fuel properly, or the fuel/air mix didn't burn as it should. The computer detects this by sensing tiny variations in crankshaft speed each time a cylinder fires. A misfire wastes fuel, raises emissions, and can damage the catalytic converter if it's severe or persistent (a flashing check engine light usually warns of active, converter-damaging misfires). Because the code points to one specific cylinder, the cause is usually an ignition, fuel, or compression problem isolated to that cylinder. Typical repair costs on GMC range from $400 to $4,500, depending on the specific model and root cause.
Common Causes of P0301
- •Worn or fouled spark plug in cylinder 1
- •Failed ignition coil or coil pack for cylinder 1
- •Faulty or clogged fuel injector for cylinder 1
- •Vacuum or intake air leak affecting that cylinder
- •Bad spark plug wire (on applicable engines)
- •Low compression (worn rings, leaking or burnt valve, head gasket)
- •Carbon buildup on intake valves
- •Wiring or connector fault to the coil or injector
P0301 on GMC by Model
GMC Canyon(1 issue)
- Active Fuel Management (AFM) Lifter Failure (V6)2015-2025
The 3.6L V6 with Active Fuel Management experiences lifter failure where the AFM lifters collapse, causing misfires and a ticking noise. The collapsing lifter can damage the camshaft lobe if not addressed.
GMC Sierra 1500(1 issue)
- Direct Injection Carbon Buildup on Intake Valves2014-2023
Direct injection engines do not spray fuel over the intake valves like port injection systems, allowing carbon deposits from oil and blow-by gases via the PCV system to accumulate on intake valve backs and ports. Over time, this buildup restricts airflow causing performance and efficiency loss. The 5.3L and 6.2L engines with direct injection are susceptible to this issue typically after 60,000-100,000 miles.
GMC Sierra 2500HD(1 issue)
- LML Duramax EGR Cooler and EGR Valve Failure2011-2016
The LML Duramax EGR (exhaust gas recirculation) cooler is prone to coolant leaks internally, allowing coolant to enter the intake manifold and combustion chambers. Coolant in the intake causes white smoke, rough running, and potential hydrolocking of cylinders. The EGR valve also sticks open or closed from carbon buildup, causing rough idle, black smoke, and check engine lights. The EGR cooler failure can occur as early as 60,000 miles on trucks used in stop-and-go driving. GM issued multiple TSBs addressing EGR cooler design improvements.
GMC Yukon XL(1 issue)
- Active Fuel Management (AFM) Lifter Failure and Tick2007-2019
The Yukon XL with the 5.3L or 6.2L V8 and Active Fuel Management (AFM/DOD) system develops hydraulic valve lifter failures. The AFM lifters, which collapse to deactivate cylinders for fuel economy, fail and cause persistent ticking noise, misfires, and potential camshaft damage. The problem is most common on 2007-2019 models. GM service bulletin recommends replacing all 8 AFM lifters if ticking persists after oil change.
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View P0301 across all makes →Frequently Asked Questions
What does P0301 mean on GMC?▼
P0301 stands for "Cylinder 1 Misfire Detected." P0301 means the engine computer detected a misfire specifically in cylinder 1 — the spark didn't ignite the fuel properly, or the fuel/air mix didn't burn as it should. The computer detects this by sensing tiny variations in crankshaft speed each time a cylinder fires. A misfire wastes fuel, raises emissions, and can damage the catalytic converter if it's severe or persistent (a flashing check engine light usually warns of active, converter-damaging misfires). Because the code points to one specific cylinder, the cause is usually an ignition, fuel, or compression problem isolated to that cylinder. On GMC specifically, this code is documented across 4 models.
What causes P0301 on GMC vehicles?▼
Common causes on GMC: Worn or fouled spark plug in cylinder 1, Failed ignition coil or coil pack for cylinder 1, Faulty or clogged fuel injector for cylinder 1, Vacuum or intake air leak affecting that cylinder, Bad spark plug wire (on applicable engines). Specific causes vary by model and year — see the per-model sections below.
How much does it cost to fix P0301 on a GMC?▼
Repair costs on GMC range from $400 to $4,500, depending on the specific model and root cause.
Which GMC models have P0301 documented?▼
Au7o has documented P0301 on 4 GMC models: Canyon, Sierra 1500, Sierra 2500HD, Yukon XL.