2010 Audi S4 Problems: 5 Known Issues
2010 model year · 107+ owner reports · Updated September 2026
According to Au7o's analysis of 107+ owner reports, the 2010 Audi S4 has 5 documented known issues, with 1 rated critical. The most serious is 0B5 DL501 S tronic Mechatronic Unit Failure - Harsh Shifts, Erratic Gear Selection and Limp Mode ($1,800-$7,000 repair). The most commonly reported issue is Thermostat Housing Failure and Coolant Leak with 107 owner reports. Across all issues with published estimates, repair costs range from $300 to $7,000. DIY maintenance guides at au7o.io.