2021 Audi S5 Problems: 6 Known Issues
2021 model year · 497+ owner reports · Updated September 2026
According to Au7o's analysis of 497+ owner reports, the 2021 Audi S5 has 6 documented known issues, with 1 rated critical. The most serious is Rear Axle Trailing Arm Eccentric Bolt Lock Nut Fracture - Recall 21V295 (Audi 42L1) ($0-$0 repair). The most commonly reported issue is Thermostat and Water Pump Assembly Failure with 211 owner reports. Across all issues with published estimates, repair costs range from $300 to $1,200. DIY maintenance guides at au7o.io.